Description

Ligandrol, also known as LGD-4033, is an orally active and highly bioavailable Selective Androgen Receptor Modulator (SARM). Initially proposed to treat muscle wasting, osteoporosis and a whole host of musculoskeletal degenerative conditions, it has the reputation of being the most potent SARM currently reviewed in clinical trials. Demonstrating the most favourable ratio of relative anabolic to androgenic activity, data indicates that it likely has the most efficacy in this class of compounds when it comes to muscle growth

Targeting androgen receptors in a highly selective way and with excellent oral bioavailability, it does not require 17 alpha-alkylation in order to be utilized by the body, thus side-stepping the liver toxicity associated with oral anabolic steroids. In fact, this high degree of tissue selectiveness allows Ligandrol to dodge the negative side effects of traditional steroids and prohormones that stem from their conversion to 5α-reduced androgens, such as increased risk of benign prostate hyperplasia, prostate carcinoma, acne breakouts, and expedited male pattern baldness. With no aromatization taking place either, estrogen -related problems, like gynecomastia, are also no issue. This vastly improved safety profile over testosterone use is exactly why Ligandrol has joined Ostarine in leading the race for clinical approval ahead of all other SARMS.

Ligandrol has a formidable reputation when it comes to gains in mass and strength, making it extremely popular with strength athletes as well as bodybuilders. Although users are divided, most claim greater overall gains with Ligandrol, whilst those attained with Rad140 tend to be drier. Whilst mg for mg, Ligandrol is stronger than Ostarine, remember that the same can also be said when comparing it with most anabolic steroids and prohormones, -just 1 mg a day yielded gains of 2.67 lbs of lean muscle in only 3 weeks in one trial, -imagine what the recommended dosage will do!

As with all other SARMS, Ligandrol LGD-4033 can still temporarily impact natural testosterone levels to a degree during and slightly after use, with levels normalizing within a couple of weeks of discontinued use provided sensible cyclic use is adhered to, with this being kept relatively short (4-8 weeks) to allow full recovery between cycles. As potentially the strongest SARM, it is advised that these guidelines are followed and that users choose to alternate use with a milder but still dependable product like ostarine.