Proviron 30 x 25mg


Proviron is a very important addition to cycles of anabolics and post cycle therapy


Proviron 30 x 25mg

Like other AAS, mesterolone is an agonist of the androgen receptor (AR).[2] Mesterolone is described as a very poor anabolic agent due to inactivation by 3α-hydroxysteroid dehydrogenase (3α-HSD) in skeletal muscle tissue, similarly to DHT and mestanolone (17α-methyl-DHT).[2] In contrast, testosterone is a very poor substrate for 3α-HSD, and so is not similarly inactivated in skeletal muscle.[2] Because of its lack of potentiation by 5α-reductase in “androgenic” tissues and its inactivation by 3α-HSD in skeletal muscle, mesterolone is relatively low in both its androgenic potency and its anabolic potency.[2] However, it does still show a greater ratio of anabolic activity to androgenic activity relative to testosterone.[2]

Mesterolone is not a substrate for 5α-reductase, as it is already 5α-reduced, and hence is not potentiated in so-called “androgenic” tissues such as the skinhair follicles, and prostate gland.[2]

Mesterolone is not a substrate for aromatase, and so cannot be converted into an estrogen.[2] As such, it has no propensity for producing estrogenic side effects such as gynecomastia and fluid retention.[2] It also has no progestogenic activity.[2]

Because mesterolone is not 17α-alkylated, it has little or no potential for hepatotoxicity.[2] However, its risk of deleterious effects on the cardiovascular system is comparable to that of several other oral AAS.[2]


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