Trimix is a non-FDA approved product for the treatment of erectile dysfunction. The only FDA approved penile injection therapy for the treatment of ED is Alprostadil, also known as Caverject, Edex or Muse. Trimix, on the other hand, is a combination of three vasoactive ingredients. The components of Trimix include Papaverine, Phentolamine, and Alprostadil. The three components together are commonly called combination therapy. Together Trimix utilizes several different mechanisms to achieve an erection, such as:

1) Increasing corporal smooth muscle relaxation

2) Decreasing smooth muscle and blood vessel contraction

3) Increasing blood vessel dilation